A new trend is emerging in the world of skin rejuvenation. Rather than chasing dramatic changes, people are increasingly seeking treatments that deliver subtle, cumulative changes that actually work to change (and help rejuvenate) the skin. Polynucleotides are a perfect example of this trend; here’s why.
Polynucleotides are unlike any other skin treatment. Placed beneath the skin and working at a cellular level, they support tissue repair, hydration and overall skin quality. And, rather than cosmetically treating the symptoms of ageing, polynucleotides aim to restore healthier skin function from within.
So, what exactly are polynucleotides?
Polynucleotides are chains of nucleotides, the building blocks of DNA. In aesthetic treatments, these molecules are highly purified and typically derived from natural sources. When introduced into the skin, they act as bio-stimulators, encouraging the body’s own regenerative processes.
Their primary role is not to fill or lift, but to address the skin’s environment. This includes enhancing hydration, promoting collagen production and supporting tissue repair. As a result, polynucleotides are often referred to as ‘bioregenerative’ treatments.
How do polynucleotides work?
Polynucleotides deliver their effects through several key mechanisms:
- Cellular regeneration: They stimulate fibroblasts, the cells responsible for producing collagen and elastin, which are essential for skin strength and elasticity.
- Hydration support: Polynucleotides have a strong affinity for water, helping to address skin hydration and maintain moisture balance.
- Anti-inflammatory effects: They can reduce inflammation, making them particularly useful for sensitive or compromised skin.
- Tissue repair: By promoting healing processes, they address skin integrity and resilience over time.
- Antioxidant activity: Polynucleotides help neutralise free radicals, which contribute to premature ageing.
When combined, these actions lead to gradual but noticeable changes in skin texture, tone and overall quality.
What can polynucleotides treat?
Polynucleotide treatments are versatile and can address a range of skin concerns, including:
- Fine lines and early wrinkles
- Dehydrated or dull skin
- Loss of elasticity
- Acne scarring
- Skin thinning, particularly around the eyes
- Sun-damaged skin
- Redness and inflammation
They are especially popular for delicate areas such as the under-eye region, where traditional volumising products may not be suitable.
Where can they be used?
Polynucleotides can be used across multiple areas of the face and body. Common treatment areas include:
- Face (cheeks, forehead, jawline)
- Under-eye area
- Neck
- Décolletage
- Hands
This ability to address skin quality without adding bulk makes them ideal for those of us who want subtle changes that deliver a refreshed appearance without altering facial structure.
What to expect during treatment
A polynucleotide treatment at Samara Aesthetics takes about 30-60 minutes. After a thorough consultation, your cosmetic nurse will then apply a topical numbing cream to help with comfort. When it has taken effect, they will carefully introduce the product into the targeted area/s. The treatment is usually well tolerated, though patients can experience mild stinging or pressure.
Following your procedure, there may be some temporary side effects, including:
- Mild swelling
- Redness
- Small bumps at treatment sites
- Occasional bruising
These effects generally resolve within a few days.
Results and treatment course
Polynucleotide treatments are not designed to provide an immediate transformation. Instead, they work gradually as the skin undergoes regeneration.
Most patients require a course of 2 – 4 treatments spaced several weeks apart. Changes typically become noticeable after the second session, with continued enhancement over time.
Results may include:
- Changes in skin texture and smoothness
- Increased hydration and radiance
- Reduction in fine lines
- Enhanced skin firmness
- Healthier, more resilient skin
Maintenance treatments are often recommended every 6 – 12 months, depending on individual goals and skin condition.
How do polynucleotides compare to other treatments?
Polynucleotides differ from other non-surgical cosmetic treatments in both the way they work and their outcomes.
- Volumising products: Volumisers add volume and structure, whereas polynucleotides address skin quality without altering facial contours.
- Skin boosters: While both aim to hydrate the skin, polynucleotides offer additional regenerative and anti-inflammatory benefits.
- Laser or energy-based devices: Polynucleotides can complement these treatments by enhancing healing and optimising results.
They are often used as part of a broader treatment plan, working synergistically with other modalities.
Am I a suitable candidate?
Polynucleotide treatments are suitable for a wide range of patients, particularly those who:
- Are experiencing early signs of ageing
- Have sensitive or damaged skin
- Want to address skin quality rather than volume
They can be used across different age groups and skin types, though they are not suitable for pregnant women.
As with any medical treatment, your suitability should be assessed during a face-to-face consultation. Patients with certain medical conditions, infections or allergies may not be appropriate candidates.
Safety and Considerations
Polynucleotides are generally considered safe when administered by a qualified practitioner such as a registered cosmetic nurse. The products used are highly purified, reducing the risk of adverse reactions.
That said, potential risks include:
- Bruising or swelling
- Infection (rare)
- Allergic reaction (very rare)
For more information about polynucleotides, please get in touch with the clinic today on 1300 726 272.
